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  • Kaletra Information

  • Kaletra Information


    Description and Usage

    Kaletra is an AIDS medication called a protease inhibitor. The active ingredient in Kaletra is lopinavir. Kaletra is available in capsule form, which also contains a small amount of the protease inhibitor Norvir (ritonavir).


    Patients who are allergic or otherwise unable to take Norvir may not be able to take Kaletra.

    Possible Side Effects

    Side effects can include diarrhea, significant increases in blood fats (cholesterol and triglycerides), liver toxicity (with increased liver enzymes), stomach pain, feeling weak or tired, headache, nausea and vomiting. People co-infected with hepatitis B and/or C may be at greater risk of developing liver toxicity from Kaletra.

    Possible Interactions

    One should check with their doctor before taking Kaletra if they are taking the following:

    Amiodarone (e.g., Cordarone); Bepridil (e.g., Vascor); Quinidine (e.g., Quinidex); Astemizole (e.g. Hismanal); Cisapride (e.g., Propulsid); Flecainide (e.g., Tambocor); Pimozide (e.g., Orap); Propafenone (e.g., Rythmol); Terfenadine (e.g., Seldane); Atorvastatin (e.g., Lipitor); Cerivastatin (e.g., Baycol); Lovastatin (e.g., Mevacor); Simvastatin (e.g., Zocor); Carbamazepine (e.g., Tegretol); Dexamethasone (e.g., Decadron); Phenobarbital (e.g., Luminal); Phenytoin (e.g., Dilantin); Clarithromycin (e.g., Biaxin); Cyclosporine (e.g., Sandimmune, Neoral); Felodipine (e.g., Plendil); Nicardipine (e.g., Cardene); Nifedipine (e.g., Procardia); Sirolimus (e.g., Rapamune); Tacrolimus (e.g., Prograf); Dihydroergotamine (e.g. D.H.E., Migranal); Ergonovine (e.g., Ergotrate); Ergotamine (e.g., Ergostat); Methylergonovine (e.g., Methergine); Midazolam (e.g., Versed); Triazolam (e.g., Halcion); Efavirenz (e.g., Sustiva); Nevirapine (e.g., Viramune); Ethinyl estradiol; Ketoconazole (e.g., Nizoral); Itraconazole (e.g., Sporonox); Rifabutin (e.g., Mycobutin); Rifampin (e.g., Rifadin); St. John's wort; Sildenafil (e.g., Viagra); Warfarin (e.g., Coumadin)

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