Essiac History Essiac was popularized in Canada during the 1920s, when the developer, a nurse from Ontario, began to advocate its use as a cancer treatment. In 1922, the developer obtained an herbal tea formula from a female breast cancer patient who claimed the mixture had cured her disease. Reviewed in [1-6] The patient reportedly received the formula from an Ontario Ojibwa Native American medicine man. The developer subsequently modified the formula, producing both injectable and oral forms of treatment. Reviewed in [2-9] From 1934 to 1942, the developer operated a cancer clinic in Bracebridge, Ontario, and dispensed Essiac free of charge. Reviewed in [10] In 1938, members of the Royal Cancer Commission of Canada visited the clinic and heard testimonials from patients who had been treated with the mixture. Reviewed in [4,8] The Cancer Commission concluded there was only limited evidence for the effectiveness of Essiac. After years of controversy, the developer closed the clinic in 1942, but continued to provide Essiac to patients until the late 1970s. Reviewed in [4,5] (See also Human/Clinical Studies.) From 1959 until the late 1970s, the developer collaborated with an American physician to conduct clinical and laboratory studies of Essiac and to promote its use. Reviewed in [4,8] This collaboration led to the development of the 8-herb formula now marketed as Flor•Essence. None of the results of these collaborative studies were reported in peer-reviewed, scientific journals. In 1977, the developer provided a 4-herb recipe for Essiac to a Canadian corporation. Reviewed in [6,8] In 1978, the corporation filed a “preclinical new drug submission” with the Canadian Department of National Health and Welfare (Health Protection Branch) and was given permission to conduct clinical studies of Essiac’s safety and effectiveness in cancer patients. Reviewed in [4-6,8,9] In 1982, this permission was withdrawn when it was determined that the corporation had not fulfilled commitments to adequately control the manufacturing consistency of Essiac, to isolate and characterize active substances in the mixture, and to design and execute appropriate clinical trials. Reviewed in [4-6] During this period, restrictions were imposed on the promotion of Essiac as a cancer treatment, but the corporation was allowed to distribute it to cancer patients through their physicians under Canada’s Emergency Drug Release Program (also called Health Canada’s Special Access Programme). Reviewed in [8] While the preclinical new drug submission was in effect in Canada, the corporation filed an unsuccessful New Drug Application (NDA) with the FDA, seeking permission to market Essiac in the United States. Details of the NDA submission, which can be disclosed only by the corporation, have not been made public. Reviewed in [5] (See also Human/Clinical Studies.) In the early 1980s, the Canadian Department of National Health and Welfare (Bureau of Human Prescription Drugs) conducted a retrospective review of case summaries submitted by physicians whose patients had obtained Essiac under the Emergency Drug Release Program. Reviewed in [2,5,8] The Department found little evidence to suggest that Essiac was effective as a cancer treatment. (See Human/Clinical Studies.) Also in the 1980s, the manufacturers of Essiac-like products began to market their formulations as health tonics and to avoid making claims of effectiveness in treating disease. Consequently, the mixtures were no longer subject to regulation as drugs. Reviewed in [4] Essiac is not currently available under Canada’s Emergency Drug Release Program. In 1995, the corporation that acquired the 4-herb recipe for Essiac from the developer dissolved voluntarily.[1] Later that year, a new company was formed to manufacture and distribute this proprietary herbal mixture.[1] Reviewed in [6] As noted previously (General Information), the proposed mechanisms of action for Essiac and Flor•Essence include strengthening the immune system, anti-inflammatory effects, and direct anticancer activity.[1,11] Reviewed in [3,4,8,9] As also noted previously (General Information), proponents of the mixtures claim these effects are dependent on the presence of the constituent herbs in the correct proportions. Reviewed in [2,7-9] It is important to note, however, that the potential for synergistic interactions between the various herbs has not been rigorously studied. References Essiac. Kirkland, Canada: Altramed Health Products, 2002. Available online. Last accessed June 16, 2004. Tamayo C: Essiac for cancer. Alternative Therapies in Women's Health 2 (3): 19-23, 2000. Locock RA: Essiac. Can Pharm J 130: 18-9, 1997. Reviews of Therapies: Herbal/plant therapies: Essiac. Houston, Tex: M.D. Anderson Cancer Center, 2002. Available online. Last accessed June 16, 2004. Herbal treatments. In: US Congress, Office of Technology Assessment.: Unconventional Cancer Treatments. Washington, DC: U.S. Government Printing Office, 1990. OTA-H-405, pp 71-5. Also available online. Last accessed June 16, 2004. LeMoine L: Essiac: an historical perspective. Can Oncol Nurs J 7 (4): 216-21, 1997. [PUBMED Abstract] Tamayo C, Richardson MA, Diamond S, et al.: The chemistry and biological activity of herbs used in Flor-Essence herbal tonic and Essiac. Phytother Res 14 (1): 1-14, 2000. [PUBMED Abstract] Kaegi E: Unconventional therapies for cancer: 1. Essiac. The Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative. CMAJ 158 (7): 897-902, 1998. [PUBMED Abstract] Essiac. Toronto, Canada: Canadian Breast Cancer Research Alliance, 1996. Available online. Last accessed June 16, 2004. The History of Essiac & Rene Caisse, Canada's Cancer Nurse. Kirkland, Canada: Altramed Health Products, 2001. Available online. Last accessed June 16, 2004. Flora Flor•Essence®. Burnaby, Canada: Flora Manufacturing & Distributing Ltd. Available online. Last accessed June 16, 2004. Read More On This Subject

Contact A Las Vegas Attorney

Neither the State Bar of Nevada nor any agency of the State Bar has certified any lawyer identified here as a specialist or as an expert.  Anyone considering a lawyer should independently investigate the lawyer's credentials and ability. This site is intended for Nevada residents and those with legal issues arising under the jurisdiction of the State of Nevada.  This site does not give legal advice or create an attorney-client relationship.  Laws are different in other states and localities, consult a local attorney. The information in this web site is provided for informational purposes only. The information does not constitute legal advice. The use of this site does not create an attorney-client relationship. Further communication with an attorney through the web site and e-mail may not be considered as confidential or privileged. Please contact our attorneys if you wish to discuss the contents of this web site. If you experience unusual problems with this site or discover dead links, please email the webmaster. Thank you.   Copyright: David Matheny, 2003-2005.